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C57BL/6JGpt-Tg(APP,hPSEN1)48/Gpt

FAD2T(APP/PS1)|Strain NO.T005625

Transgenic (Tg)

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BASIC INFORMATION
Strain Name: C57BL/6JGpt-Tg(APP,hPSEN1)48/Gpt
Strain Number: T005625
Official Symbol: App,Psen1
Strain Strategy: T005625.FAD2T(APP PS1) strain info.pdf
Official Full Name: amyloid beta (A4) precursor protein,presenilin 1
Also Known As: Ag,Abpp,Adap,Cvap,Abeta,betaApp,E030013M08Rik,PS1,Ad3h,PS-1,S182
NCBI Number: 1182019164
Research Areas: Disease Models,Neurodegenerative diseases,Alzheimer's disease
Strain Background: [N000013] C57BL/6JGpt
Modification Type: Transgenic (Tg)
Inventory Status: Live,Cryopreserved
Sale Status: IF (Available for Distribution)
Health Status: Specific pathogen free (SPF)
Health Report: Please log in to view
Publications: 1. Icariin improves learning and memory function by enhancing HRD1-mediated ubiquitination of amyloid precursor protein in APP/PS1 mice. Journal of Alzheimer's disease : JAD (2025)2. Radiofluorination of 2-Arylquinolin-4-yl Oxypropanamide Derivatives for TSPO Imaging in Neuroinflammatory Murine, Nonhuman Primates, and Human Brain Autoradiography with Insensitivity to the rs6971 Polymorphism. Journal of medicinal chemistry (2025)3. Late-Stage Activation of Toll-like receptor 3 Alleviates Cognitive Impairment and Neuropathology in an Alzheimer's Disease Mouse Model. Molecular neurobiology (2025)4. Calycosin improved long-term memory impairment in the very early of APP/PS1 mice. Brain research (2025)